Apalutamide is the First Agent Submitted for Approval to Treat Earlier Stage Castration-Resistant Prostate Cancer at High Risk for Metastasis

Clinicians are challenged with a multitude of treatment options for patients with castration-resistant prostate cancer (CRPC). To assist in clinical decision-making, six index patients were developed representing the most common clinical scenarios that are encountered in clinical practice.

Janssen Submits New Drug Application to U.S. FDA for Apalutamide (ARN-509) to Treat Men with Non-Metastatic Castration-Resistant Prostate Cancer

Castration-resistant prostate cancer does not necessarily require the presence of testosterone and growth in the absence of hormonal stimulation is frequently observed.

In this expert interview, Dr. Susan Slovin highlights new findings from ASCO 2008 and discusses key challenges facing clinicians who manage patients with castration-resistant prostate cancer.

Administration of docetaxel every 2 weeks seems to be well tolerated in patients with castration-resistant advanced prostate cancer and could be a useful option when 3-weekly single-dose administration is unlikely to be tolerated.

Freud advanced a theory of personality development that centered on the effects of the sexual pleasure drive on the individual psyche. At particular points in the developmental process, he claimed, a single body part is particularly sensitive to …

Chemical castration is a procedure wherein medications are administered to reduce testosterone levels. This punishment is granted to sexual offenders in some countries.

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The purpose of this study is to determine how patients with metastatic castration-resistant prostate cancer, and evidence of a homologous recombination gene deficiency, respond to treatment with rucaparib.